Peripheral leptin regulates bone formation
نویسندگان
چکیده
منابع مشابه
Leptin Regulates Bone Formation via the Sympathetic Nervous System
We previously showed that leptin inhibits bone formation by an undefined mechanism. Here, we show that hypothalamic leptin-dependent antiosteogenic and anorexigenic networks differ, and that the peripheral mediators of leptin antiosteogenic function appear to be neuronal. Neuropeptides mediating leptin anorexigenic function do not affect bone formation. Leptin deficiency results in low sympathe...
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Comparative study of bone and lamellar bone formation in Peripheral Giant Cell Granuloma and Peripheral Ossifying Fibroma Dr. SH. Ghasemi Moridani* - Dr. H. Mahmoodi Chenari* *-Assistant Professor of Oral and Maxillofacial Pathology Dept.-Faculty of Dentistry-Guilan University of Medical Sciences. **- Dentist. Background and Aim: Peripheral Giant Cell Granuloma (PGCG) and peripheral ossifying f...
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Glucocorticoid therapy, especially at higher doses, is associated with significant adverse side effects including osteoporosis. Leptin, secreted from adipose tissue, has diverse effects on bone tissue regulation. As glucocorticoids stimulate leptin synthesis and secretion directly in adipose tissue we hypothesised that dexamethasone (DEX) induced osteoporosis may, in part, be mediated by an ost...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2012
ISSN: 0884-0431
DOI: 10.1002/jbmr.1734